The Random Present — Ketones for Cognition, Tim’s Finest Lab Leads to 10+ Years, How Kevin Hit 100 Days Sober, Residence Protection, Vibe Coding Unleashed, and Extra (#822)

Welcome to a different wide-ranging “Random Present” episode I recorded with my shut pal Kevin Rose (digg.com)!

We cowl Kevin’s sobriety journey and marking 100 days with out alcohol, my outcomes with the ketogenic weight-reduction plan and intermittent fasting, GLP-1 agonists, residence protection and safety, the way forward for Enterprise Capital, authenticating your self on-line, AI, the cultural shift towards human-to-human connection, Roblox, and extra.

Please take pleasure in!

Hearken to the episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Castbox, YouTube Music, Amazon Music, Audible, or in your favourite podcast platform. Watch the dialog on YouTube. The transcript of this episode might be discovered right here. Transcripts of all episodes might be discovered right here.

This episode is delivered to you by Momentous high-quality creatine to sharpen the thoughts; David Protein Bars with 28g of protein, 150 energy, and 0g of sugar; and AG1 all-in-one dietary complement.

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This episode is delivered to you by Momentous high-quality creatine and extra! Momentous presents high-quality dietary supplements and merchandise throughout a broad spectrum of classes, and I’ve been testing their merchandise for months now. I’ve been utilizing their magnesium threonate, apigenin, and L-theanine each day, all of which have helped me enhance the onset, high quality, and length of my sleep. I’ve additionally been utilizing Momentous creatine, and whereas it definitely helps bodily efficiency, together with poundage or wattage in sports activities, I exploit it primarily for psychological efficiency (short-term reminiscence, and so forth.). In reality, a brand new pilot examine in Alzheimer’s sufferers, discovered that supplementing can improve mind creatine ranges by 11% in simply 8 weeks and enhance measures of reminiscence, reasoning, and a spotlight—domains that usually decline over time.

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Wish to hear the final time KevKev and I did one among these Random Reveals? Hearken to our dialog right here through which we mentioned sustaining sobriety with a associate who nonetheless drinks, Taiwanese tea, discovering magic within the unusual, the ups and downs of accelerated TMS, the intersection of AI and life sciences, deepfaked facet hustlers, when meditation retreats go proper (and unsuitable), and far more.

SELECTED LINKS FROM THE EPISODE

Web site | Instagram | Twitter | Threads | Bluesky | Digg.com

The transcript of this episode might be discovered right here. Transcripts of all episodes might be discovered right here.

Folks

• Sigmund Freud: Austrian neurologist and founding father of psychoanalysis who revolutionized our understanding of the human psyche.
• Hokusai: Japanese ukiyo-e artist of the Edo interval, well-known for “The Nice Wave off Kanagawa” and influential woodblock prints.
• Craig Mod: Author, photographer, and writer recognized for his considerate explorations of Japan, strolling, and digital publishing.
• Liam Neeson: Irish actor recognized for dramatic roles in movies like Schindler’s Record and motion movies just like the Taken sequence.
• Johnny Depp: American actor recognized for eccentric characters together with Captain Jack Sparrow and Willy Wonka in Tim Burton’s adaptation.
• Gene Wilder: American actor and comic well-known for his iconic portrayal of Willy Wonka within the 1971 traditional movie.
• Dr. Rhonda Patrick: PhD scientist and host of the FoundMyFitness podcast, specializing in vitamin, growing old, and well being optimization.
• Martin Berkhan: Health professional and founding father of the Leangains intermittent fasting protocol that revolutionized versatile weight-reduction plan.
• Dr. Peter Attia: Doctor and longevity professional specializing in the science of healthspan and lifespan optimization.
• Desmond Tutu: South African Anglican archbishop and Nobel Peace Prize winner famend for his anti-apartheid activism.
• Taran Butler: Aggressive shooter and founding father of Taran Tactical Improvements, recognized for customized firearm modifications.
• Keanu Reeves: Canadian actor beloved for roles in The Matrix trilogy and the John Wick motion franchise.
• Jim Jefferies: Australian humorist and actor recognized for his provocative and observational comedy fashion.
• Steven Seagal: American actor, screenwriter, and martial artist recognized for motion movies within the Eighties and Nineteen Nineties.
• Marc Andreessen: Co-founder of Andreessen Horowitz enterprise capital agency and co-creator of the Mosaic internet browser.
• Josh Cook dinner: Digital strategist and entrepreneur recognized for his work in know-how and social media engagement.
• Sam Altman: CEO of OpenAI and outstanding determine in synthetic intelligence growth and governance.
• Alexis Ohanian: Co-founder of Reddit and enterprise capitalist targeted on early-stage know-how investments.
• Justin Mezzell: Digg CEO, designer, and inventive director recognized for his distinctive illustration fashion and branding work.

Films, TV, and Media

• Shaun of the Useless: A 2004 British horror-comedy movie that brilliantly parodies zombie films whereas delivering real scares and laughs.
• Jason Bourne: An action-thriller movie sequence following the amnesiac super-spy created by Robert Ludlum, starring Matt Damon.
• Snatch: A 2000 British crime-comedy movie by Man Ritchie that includes interconnected felony plots and memorable characters.
• Babe: A 1995 household comedy-drama a few pig who learns to herd sheep, combining live-action with groundbreaking animatronics.
• The Bare Gun: A comedy movie sequence starring Leslie Nielsen because the bumbling Detective Frank Drebin, recognized for its slapstick humor.
• Taken: An action-thriller movie sequence starring Liam Neeson as a former CIA operative with “a really explicit set of expertise.”
• Willy Wonka & The Chocolate Manufacturing unit: A 1971 musical fantasy movie starring Gene Wilder because the eccentric chocolatier in Roald Dahl’s beloved story.
• John Wick: An motion movie sequence starring Keanu Reeves as a legendary murderer looking for vengeance, recognized for stylized combat choreography.
• Gradual TV: A tv style that includes real-time, unedited protection of prolonged occasions like prepare journeys or knitting marathons.
• Playboy: An American males’s way of life and leisure journal based by Hugh Hefner in 1953.
• Wired: A month-to-month journal protecting how rising applied sciences impression tradition, the economic system, and politics.

Books

• The 4-Hour Workweek by Timothy Ferriss: A step-by-step information to escaping the 9-5 grind by way of life design, automation, and the rules of working smarter reasonably than more durable.
• The 4-Hour Physique by Timothy Ferriss: An unusual information to fast fat-loss, unimaginable intercourse, and turning into superhuman by data-driven physique hacking and minimally efficient dose rules.
• The 4-Hour Chef by Timothy Ferriss: A meta-learning handbook disguised as a cookbook that teaches the way to grasp any ability rapidly utilizing cooking because the automobile for accelerated studying rules.

Manufacturers, Corporations, and Merchandise

• Nanoblocks: A micro-sized constructing block system from Japan that makes LEGO appear like big boulders.
• LEGO: A line of plastic building toys that naked toes have been stepping on since 1958.
• Coyote: A card sport I made for strategic considering and decision-making.
• Qitone: A model of ketone complement powder for metabolic optimization.
• N.O.-Xplode: A pre-workout complement that guarantees to show your health club session right into a managed explosion.
• Bronkaid / Primatene Mist: Over-the-counter medicines containing ephedrine for respiratory aid.
• Belsomra: A prescription sleep remedy (a DORA) that helps quiet the mind’s wake sign.
• Mounjaro / Zepbound: Model names for Tirzepatide, a GLP-1 agonist remedy for diabetes and weight administration.
• Thorne: A well being and know-how firm that sells research-backed dietary supplements.
• Taser: A model of carried out vitality weapon manufactured by Axon Enterprise.
• Ring: A house safety and sensible residence firm owned by Amazon.
• Taran Tactical: A firearms coaching firm specializing in aggressive taking pictures methods.
• Anduril: A protection know-how firm constructing autonomous methods for navy functions.
• Cloudflare: An online infrastructure and web site safety firm that retains the web working easily.
• Instruments for Humanity: The corporate behind Worldcoin and the retina-scanning Orb for world id verification.
• Oura Ring: A wise ring that tracks sleep and bodily exercise with spectacular accuracy.
• Peloton: An train tools and media firm that introduced the boutique health expertise residence.
• Fitbit: An organization producing exercise trackers and smartwatches, now owned by Google.
• Domino’s Pizza: An American multinational pizza restaurant chain recognized for supply innovation.
• Coca-Cola: A multinational beverage company that has been refreshing the world since 1886.
• Andreessen Horowitz (a16z): A enterprise capital agency that backs daring entrepreneurs constructing the long run.
• True Ventures: A enterprise capital agency targeted on early-stage know-how firms.
• Roblox: A web-based sport platform and sport creation system the place customers construct digital worlds.
• Amazon / Amazon Prime / Amazon Pharmacy: E-commerce and know-how firm that began with books and now sells every little thing.
• Costco: A multinational company that operates a series of membership-only big-box retail shops.
• Walmart / Goal: Multinational retail firms competing for America’s buying {dollars}.
• UPS: A multinational transport and receiving and provide chain administration firm in distinctive brown vans.
• 1-800-FLOWERS: A floral and gourmand meals reward retailer that pioneered phone-based ordering.
• Etsy: An e-commerce web site targeted on handmade or classic objects and craft provides.
• Bugatti: A luxurious sports activities automotive producer that creates automotive artwork for the ultra-wealthy.

Establishments and Organizations

• Alcoholics Nameless (AA): A global fellowship of people that share their expertise, power and hope with one another that they might resolve their widespread drawback and assist others to recuperate from alcoholism.
• Stanford College: A personal analysis college in Stanford, California, based in 1885 and constantly ranked among the many world’s prime tutorial establishments.
• Johns Hopkins College: A personal analysis college in Baltimore, Maryland, based in 1876 and broadly thought-about America’s first analysis college.
• TSA (Transportation Safety Administration): A federal company throughout the US Division of Homeland Safety accountable for defending the nation’s transportation methods and making certain freedom of motion for folks and commerce.

Web sites, Platforms, and Apps

• Leangains: Martin Berkhan’s web site on intermittent fasting.
• YouTube: A web-based video sharing and social media platform.
• TikTok: A brief-form video internet hosting service.
• Instagram: A photograph and video sharing social networking service.
• Fb: A web-based social media and social networking service.
• Reddit: A social information aggregation, content material score, and dialogue web site.
• Wikipedia: A free, multilingual on-line encyclopedia.
• Digg: A information aggregator with a curated entrance web page.
• Coyote: The official web site for the cardboard sport Coyote.
• River: An in-person occasion and social platform for communities.
• Cursor / Claude Code: AI-powered coding instruments.
• Lovable (previously Base44): “Vibe coding” platforms for constructing apps.
• Vercel: A cloud platform for frontend frameworks and static websites.

Ideas and Phrases

• 12-Step Applications: A set of guiding rules for restoration from habit, most famously utilized by Alcoholics Nameless and different restoration organizations worldwide.
• Ketogenic Food plan (Keto): A high-fat, low-carbohydrate weight-reduction plan that forces the physique to burn fats for gasoline as a substitute of glucose, initially developed to deal with epilepsy.
• Intermittent Fasting (16/8): An consuming sample that cycles between intervals of consuming and fasting, with the 16/8 methodology involving 16 hours of fasting and an 8-hour consuming window.
• Zone 2 Coaching: Low-intensity cardio train carried out at a particular coronary heart fee zone that maximizes fats burning and mitochondrial effectivity.
• APoE (Apolipoprotein E) Gene: A gene related to the chance of creating Alzheimer’s illness, with the APOE4 variant considerably rising susceptibility to cognitive decline.
• Oral Glucose Tolerance Check (OGTT): A medical take a look at to evaluate how the physique processes glucose over time, generally used to diagnose diabetes and prediabetes.
• ApoB (Apolipoprotein B): A main protein part of LDL (“dangerous”) ldl cholesterol particles, thought-about a extra correct marker for heart problems threat than conventional ldl cholesterol assessments.
• Autophagy: The physique’s mobile “housekeeping” technique of breaking down and recycling broken proteins and organelles to keep up mobile well being and longevity.
• Exogenous Ketones: Ketone dietary supplements taken orally to quickly induce ketosis with out following a strict ketogenic weight-reduction plan, although their effectiveness stays debated.
• GLP-1 Agonists: A category of medicines that mimic the hormone GLP-1, used for treating sort 2 diabetes and weight problems by regulating blood sugar and urge for food.
• DORA (Twin Orexin Receptor Antagonist): A more recent class of sleep medicines that work by blocking orexin receptors within the mind to advertise pure sleep patterns with fewer unwanted effects than conventional sleep aids.
• ECA Stack: A controversial and now largely banned complement mixture of ephedrine, caffeine, and aspirin as soon as standard amongst bodybuilders for fats loss however related to critical well being dangers.
• Vibe Coding: A contemporary method to programming that depends closely on AI instruments and intuitive problem-solving reasonably than conventional pc science fundamentals, enabled by superior code technology AI.
• Useless Web Principle: A conspiracy idea suggesting that the web is now predominantly populated by bots and AI-generated content material reasonably than genuine human interplay.
• ZK Proofs (Zero-Information Proofs): A cryptographic methodology that enables one celebration to show they know particular data with out revealing the knowledge itself, essential for privacy-preserving blockchain functions.
• DEXA Scan: A low-radiation X-ray scan that exactly measures bone density, physique fats share, and lean muscle mass, thought-about the gold commonplace for physique composition evaluation.
• Enterprise Capital: A type of non-public fairness financing the place traders present capital to startups and early-stage firms with excessive development potential in alternate for fairness possession.

SHOW NOTES

• [00:00:00] Begin.
• [00:06:54] Kevin celebrates 100 days sober! Why and the way?
• [00:15:16] Nanoblocks: Kevin’s new Japanese micro-building interest.
• [00:18:16] The Gradual TV motion and Craig Mod’s ambient recordings.
• [00:20:58] Craving analog experiences and wilderness trekking.
• [00:22:24] Writing with background films.
• [00:23:42] Excessive hopes for The Bare Gun reboot.
• [00:24:35] Kevin’s improved communication since quitting alcohol.
• [00:26:28] My well being interventions for cognitive safety.
• [00:29:00] How ketogenic weight-reduction plan and 16/8 intermittent fasting led to my finest lab ends in 10+ years.
• [00:33:35] Weight management regimens we don’t advocate.
• [00:39:51] Exogenous ketones: Qitone vs. premium choices.
• [00:50:32] How glucose tolerance assessments work.
• [00:51:58] Microdosing GLP-1 (tirzepatide) for glucose management.
• [00:54:12] DORA sleep medicines and neuroprotective results.
• [00:56:55] Belsomra trial and value concerns.
• [00:57:52] Sauna temperature optimization based mostly on Rhonda Patrick’s analysis.
• [01:00:28] There aren’t any organic free lunches.
• [01:03:27] The time Kevin discovered a homeless particular person in his closet.
• [01:06:11] Trendy residence safety and privateness measures.
• [01:19:42] Pondering how we survived childhood.
• [01:24:23] AI-driven enterprise capital panorama adjustments.
• [01:28:59] Vibe coding revolution: $250k initiatives now price $50.
• [01:34:28] Schooling recommendation for youths within the AI age.
• [01:36:27] Empowering artistic minds vs. conventional technical roles.
• [01:38:29] What Kevin’s crystal balls say about Cloudflare’s information market for content material creators.
• [01:42:02] The Digg reboot with Alexis Ohanian: a deal with in-person connections.
• [01:42:59] Useless web idea and bot content material proliferation.
• [01:43:25] Verifying humanity: the belief gradient.
• [01:54:28] My aid on the profitable launch of Coyote.
• [01:58:03] Kevin’s Roblox habit and Develop a Backyard bills.
• [01:59:56] Future meetup plans and parting ideas.